Side Effects of Apretude: An Overview and Guidelines for Management
In the ongoing battle against HIV, a new weapon has emerged in the form of Apretude, a brand-name injection used for HIV prevention in certain adults and adolescents. This article aims to shed light on the less common and rare side effects of Apretude, as well as some important considerations for its use.
Beyond the commonly known side effects such as weight gain, headache, depression, and injection site reactions, patients on Apretude may experience a range of less common or rare effects. These can include fatigue, fever, nausea, diarrhea, dizziness, insomnia, and skin reactions like rash or itching [1].
However, it's important to note that serious rare side effects require immediate attention. These include liver problems, severe muscle damage (rhabdomyolysis), and allergic reactions, which can manifest as rash, mouth sores, breathing difficulties, or swelling in facial areas [1].
For those who drink alcohol, it's advisable to discuss with your doctor about the safety of consuming any amount during treatment with Apretude, as alcohol can increase the risk for certain side effects such as nausea, vomiting, dizziness, headache, and liver problems.
The safety of Apretude during pregnancy and breastfeeding is not yet fully established. While animal studies suggest that the drug may cause congenital anomalies or pregnancy loss, and may be present in breast milk, these findings may not necessarily apply to humans [1].
Common side effects of Apretude include fever, nausea, vomiting, sleep disorders, injection site reactions, headache, insomnia, and fatigue. Headaches were among the most common side effects reported in Apretude's clinical trials.
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Before starting treatment with Apretude, a person will be tested for HIV, and an HIV test will be recommended before each injection. If a person tests positive for HIV while receiving Apretude, they will be recommended to stop treatment and start an HIV treatment plan instead.
Apretude has a boxed warning for the risk of drug resistance when used for PrEP in certain people. If symptoms of HIV develop while receiving Apretude, the person should tell their doctor right away.
It's crucial to discuss any concerns about side effects or potential risks with your doctor. They can provide guidance on managing these effects and determining whether Apretude is the right choice for you. If depression or changes in mood are experienced, it's important to talk with your doctor right away. They can recommend the best ways to manage your symptoms and may suggest switching to another medication for PrEP if necessary.
In conclusion, while Apretude offers a valuable tool in the fight against HIV, it's essential to understand its potential side effects and considerations. By being informed and open with your doctor, you can make the best decisions for your health.
[1] For more information about Apretude's side effects, refer to Apretude's prescribing information. For more general information about Apretude, including its uses, see this "Apretude overview" article.
- Some less common side effects of Apretude may include fatigue, fever, nausea, diarrhea, dizziness, insomnia, and skin reactions like rash or itching.
- Serious and rare side effects of Apretude require immediate attention and can include liver problems, severe muscle damage, allergic reactions, and changes in mood.
- For those who drink alcohol, it's advisable to consult with a doctor about the safety of consuming any amount while undergoing treatment with Apretude.
- The safety of Apretude during pregnancy and breastfeeding is not yet fully established, and further research is needed to determine any potential risks.
- If you are using Apretude for HIV prevention, it's essential to discuss any concerns about side effects or potential risks with your doctor, who can help manage the effects and determine if the medication is right for you.
