Inherited Genes Boost Breast Cancer Risk: Know Your Family History
A doctor or genetic specialist can determine if a person has inherited breast cancer genes, which can increase the risk of developing the disease. Family history plays a significant role, with first-degree relatives posing a higher risk than second-degree relatives. Regular mammogram screenings are crucial, especially for those with a family history.
Genetic testing panels can assess multiple genes, not just BRCA. Besides BRCA1 and BRCA2, other genes like TP53, PTEN, CHEK2, ATM, PALB2, and CDH1 can also elevate the risk. Women with BRCA 1 or 2 mutations have a significantly higher chance of developing breast cancer, over 60%, compared to the general population's 13%. Men with these mutations also face an increased risk, though it's lower than in women. Regular screenings are vital, especially for those with a family history, as other genes like CHEK2 can also double the risk.
Inherited breast cancer genes can significantly increase the risk of developing the disease. Regular screenings and genetic testing can help manage this risk. Understanding family history and the role of various genes can empower individuals to take proactive steps in their healthcare.
