Experiencing issues with Leqvio? Learn about its potential side effects and ways to manage them.
Leqvio, a subcutaneous injection, has been approved by the FDA to help lower low-density lipoprotein (LDL) cholesterol levels. This medication, known chemically as inclisiran, is prescribed for adults with hyperlipidemia, including high cholesterol or heterozygous familial hypercholesterolemia.
Leqvio is typically used in combination with a low cholesterol diet and statin medication. It's important to note that Leqvio, when used alone, does not directly cause weight gain or weight loss. However, following a low cholesterol diet as part of Leqvio treatment may lead to weight loss in some people.
Clinical trials involving thousands of patients treated with inclisiran have not identified long-term safety concerns. The most commonly reported side effects are generally mild and temporary, including injection site reactions (such as pain, bruising, itching, and discoloration), joint pain, and bronchitis. Serious adverse reactions are uncommon but may include severe injection site reactions or allergic responses.
Symptoms of diarrhea, a common side effect reported in Leqvio's clinical trials, may include dizziness, dark-colored urine, and fatigue. If you experience such symptoms, it's advisable to consult your healthcare provider.
Pain in the arms and legs was a common side effect in Leqvio's clinical trials. Symptoms of pain in the arms and legs may include pain in the hands, legs, and feet. If you experience serious side effects while using Leqvio, call your doctor immediately.
Injection site reactions, such as pain, redness or discoloration, or a rash at the site of your injection, were common side effects in Leqvio's clinical trials. If you have questions about managing your weight during Leqvio treatment or if you develop a side effect while using Leqvio and want to report it to the FDA, visit MedWatch.
It's essential to remember that while short-term side effects like joint pain and injection site irritation may occur, there is no evidence of significant long-term side effects associated with Leqvio in adults with hyperlipidemia based on current clinical data.
However, if you experience any new or worsening effects that are persistent or bothersome, talk with your doctor. Serious side effects of Leqvio include shortness of breath, severe injection site reaction, and allergic reaction (with symptoms such as rash, angioedema, and trouble breathing). For mild allergic reaction symptoms, call your doctor right away. For severe allergic reaction symptoms, call 911 or your local emergency number right away.
In summary, Leqvio offers a new treatment option for managing high cholesterol levels. While it's crucial to be aware of potential side effects, the current clinical data suggests that it is generally well-tolerated and does not have any significant long-term side effects. As with any medication, it's essential to discuss any concerns with your healthcare provider.
