Covid-19 Vaccines Identified as Potential Triggers for Cardiac Arrests
A new study led by German scientists has raised concerns about the potential for cardiac damage caused by mRNA COVID-19 vaccines. The research, published in the medical journal Frontiers in Immunology, suggests that the intracellular aggregation of spike protein subunits in heart cells plays a key role in the development of myocarditis and other inflammatory cardiac events following vaccination.
The study delved into the molecular behaviour of spike proteins produced by mRNA vaccines, such as Pfizer/BioNTech and Moderna. Within hours of receiving the injection, the study observed that the spike proteins started clumping together into large, sticky aggregates inside the cells.
The researchers found that both Pfizer and Moderna's mRNA "vaccines" prompt cells to produce two versions of the spike protein monomer, small protein units that initiate an immune response. However, the S1 subunit, the key piece that stimulates the immune response, escapes the cells and moves into the surrounding environment, while the other spike protein components, including the sticky aggregates, remain trapped inside the heart cells.
This mechanism serves as a trigger behind myocarditis and other cardiac events reported following mRNA "vaccination." The study's findings raise serious questions about how the body is processing and handling spike proteins after vaccination, particularly in susceptible individuals.
Current evidence indicates that mRNA COVID-19 vaccines are associated with a rare risk of myocarditis and pericarditis, particularly in younger males aged 12 to 24 years. The FDA updated safety labeling in June 2025 to warn about myocarditis and pericarditis after mRNA vaccines, noting about 27 cases per million doses in young males, with some patients showing persistent signs of myocardial injury on cardiac MRI about 5 months post-vaccination.
However, no compelling evidence supports a mechanism involving spike protein aggregation within heart cells as a cause of cardiac injury or arrests. Myocarditis following mRNA vaccination is thought to be an inflammatory or immune-mediated reaction, not linked to spike protein aggregation per se.
The need for more research into the long-term effects of these vaccines remains critical, particularly as more data emerges about their impact on different age groups and underlying health conditions. Vaccine manufacturers and health authorities must continue to monitor these risks and ensure transparency as more data becomes available.
In human heart cells, or cardiomyocytes, the spike protein clusters cause significant disruption, hindering cell growth, triggering oxidative stress, and initiating an inflammatory response, typical signs of early-stage myocarditis. The study adds to the growing concerns about the potential for cardiac damage caused by mRNA "vaccines."
[1] FDA-sponsored multi-institutional study of 333 patients hospitalized with vaccine-associated myocarditis. [2] European study reviewing myocarditis and pericarditis risks after mRNA-1273 vaccination. [3] Epidemiological data from large cohort studies showing no increased risk of adverse cardiac events after updated mRNA vaccines incorporating the Omicron JN.1 lineage. [4] Studies underscoring overall cardiovascular safety but reaffirming myocarditis and pericarditis as recognized albeit rare risks, mostly with early formulations in younger populations.
- The study's findings on the intracellular aggregation of spike protein subunits in heart cells contribute to growing concerns about the potential for cardiac damage caused by mRNA COVID-19 vaccines like Pfizer/BioNTech and Moderna.
- The molecular behavior of spike proteins produced by these vaccines may cause significant disruption in human heart cells, leading to cell growth hindrance, oxidative stress, and an inflammatory response, typical signs of early-stage myocarditis.
- While current evidence suggests that myocarditis following mRNA vaccination is mainly an inflammatory or immune-mediated reaction, not linked to spike protein aggregation per se, the need for more research into the long-term effects of these vaccines, particularly in relation to health-and-wellness, medical-conditions, and cardiovascular-health, remains critical.
